X-Message-Number: 16915
Date: Sat, 7 Jul 2001 08:43:00 -0700
Subject: Cell Rejuvenation Therapy
From: Ivan Snyder <>

Hi friends,

I attended cryonicist Kat and David Kekich's wedding in Palos Verdes CA
last weekend and had a great time. Absent minded as I am, I neglected to
bring a wedding present. I hope the following information will do and be
of some value. At the wedding reception I spoke to Carla who now works at
Cells 4-Life. As a science enthusiast, I am keen to keep up with the
latest discoveries and am ever mindful as to where these might lead.
Carla was not aware a particular finding (*below), which I find most
exciting. I'm not the only one. Here is a snip from a newpaper article
yesterday. "The most exciting scientific news in recent years is that the
human body may have the capacity to regenerate itself. Biologists were
stunned: Degeneration is not inexorable. Stem cells soon may be directed
to repair organs and rejuvenate those that are wearing out;" William
Safire. Anyway, I think we need to discuss this matter here and now to
prepare ourselves. Below is more info I have assembled.
Ivan Snyder
Hermosa Beach
California

STEM CELL REJUVENATION THERAPY 

Cloning
Cloned cells are rejuvenated. Cloning resets the biological clock back to
conception. Dolly's (the first cloned sheep) clone was a rejuvenated
copy. Dolly's clone will live another complete life span. *Some
researchers thought the clone's teleomeres were shortened, meaning that
the clone was of the same biological age as Dolly. Not true, the clone
gave birth. Sheep do not remain reproductive so long. This all means we
now in fact have a way to rejuvenate cells, and more than that:  

Stem Cells For Repair
Cloned cells can be made into embryonic stem cells. Stem cells are
undifferentiated cells which when incorporated into some other specific
tissue will be converted into that tissue. Stem cells are currently being
used to repair injury in different organs. In test animals, stem cells
injected into damaged hearts have replaced a high percentage of whole
hearts. Stem cells have also successfully replaced bone marrow. The
benefit of using stem cells made from one's own body is that these are
not rejected. We now have the technology to replace aging tissue with
rejuvenated cells. The next step is rejuvenation of an entire body. Below
is one direction for further research.

Metastasis and Normal Replacement
It is well known that cancer cells can split off from a cancerous growth
and migrate through the bloodstream and grow new cancers where they
anchor. A less known fact is that normal cells too can detach from one
site, migrate through the bloodstream and become incorporated into
another organ. Also, a normal ongoing cell activity is the replacement of
older or damaged cells by healthy younger cells. The younger cells will
actually digest and replace adjacent unhealthy cells. 

Stem Cell Transfusion?
The above is a clue to total rejuvenation and how embryonic stem cells
might be delivered throughout the body. It is seen that cells can
metastasize by migrating through the bloodstream. Could then a suspension
of stem cells be simply transfused into the blood, lymph, and spinal
fluid and be effective in total cell replacement if administered slowly
over a long period? Sound crazy? We can't say yet how effective this
might be on Humans yet, but we may infer from nature with other animals.
In salamanders having amputated limbs it is blood cells (nucleated) which
are converted into the newly forming embryonic limb at the injury site.
These creatures remember are able to regenerate entirely new limbs and
other organs. 

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