X-Message-Number: 22437
From: 
Date: Sat, 30 Aug 2003 10:25:35 EDT
Subject: four-amino-acid peptide telomerase activator

There's an abstract from a Russian group that claims a peptide can turn on 
telomerase:


1: Bull Exp Biol Med. 2003 Jun;135(6):590-2.    <A 
HREF="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Display&dopt=pubmed_pubmed&from_uid=12937682">Related
Articles,</A> >Links</A>     

Epithalon Peptide induces telomerase activity and telomere elongation in 
human somatic cells.

Khavinson VKh, Bondarev IE, Butyugov AA.

St. Petersburg Institute of Bioregulation and Gerontology, North-Western 
Division of Russian Academy of Medical Sciences. 

Addition of Epithalon peptide in telomerase-negative human fetal fibroblast 
culture induced expression of the catalytical subunit, enzymatic activity of 
telomerase, and telomere elongation, which can be due to reactivation of 

telomerase gene in somatic cells and indicates the possibility of prolonging 
life 
span of a cell population and of the whole organism.

PMID: 12937682 [PubMed - in process]    

Our med library doesn't get this journal. Anyone seen this paper (or the 
similar paper from the Cold Spring Harbor meeting?)



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