X-Message-Number: 22472
Date: Fri, 5 Sep 2003 21:39:40 -0700 (PDT)
From: Doug Skrecky <>
Subject: 102'nd update on fly longevity experiments

    This is the 102'nd update of my fly longevity experiments. Average
temperature was 23.3 C during this run. Estimated maximal longevity using
the formula (363 - T*11.2) is 102 days.
    Starting with this run, dark storage conditions are standard. Here I
reexamine at higher doses oxymol, and sour cherry syrups, as well as take
a first look at raspberry syrup. Oxymol has previously improved survival
at a 2 teaspoon dose in run #98, and sour cherry was beneficial at 1 tsp
in run #93.
    Oxymol this time yielded only a modest advantage at a 2 tsp dose, late
in the experiment. Higher doses proved to be toxic. Sour cherry was also
helpful at a 2 tsp dose, but 4 tsp was toxic. Raspberry was also slightly
beneficial at the lower doses. In all these cases there appears to be a
narrow therapeutic range, with effective doses becoming rapidly toxic at
higher doses. [However the remaining raspberry syrup did prove to be
delicious.]
    Starting with the next run I'll be testing the effect of raw vegetable
extracts found at local supermarkets.

Run #102                      Percent Survival on Day
supplement                 5  10  15  21 26 31 38 44 49 54 60 66
________________________________________________________________
control one              100 100  92  92 92 77 62 15  0  -  -  -
control two               94  94  94  69 69 63 31 19 19  6  6  0
oxymol 2 tsp             100  92  92  83 75 67 50 38 33 17  0  -
oxymol 4 tsp              96  87  87  83 78 70 39  4  0  -  -  -
oxymol 6 tsp              94  94  88  69 63 50 13  0  -  -  -  -
raspberry syrup 2 tsp    100  95  95  90 90 71 57 33 24  5  0  -
raspberry syrup 4 tsp    100 100  96  96 91 91 57 30 17  0  -  -
raspberry syrup 6 tsp    100 100 100  94 89 44  6  0  -  -  -  -
sour cherry syrup 2 tsp  100  95  95  95 95 89 63 53 21 11  0  -
sour cherry 4 tsp        100 100 100 100 95 84 32  5  5  0  -  -

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