X-Message-Number: 23167
From: "mike99" <>

Subject: FW: Tricked Brain Cells Live Hours without Oxygen [Transhumanity - 
daily newsletter]
Date: Fri, 26 Dec 2003 17:58:52 -0700

Good news for delaying ischemia.

-----Original Message-----
From:  [mailto:]

[ News ] Tricked Brain Cells Live Hours without Oxygen

		From <a
href="http://www.betterhumans.com/News/news.aspx?articleID=2003-12-24-4">Bet
terhumans</a>: Exploiting their discovery about a mechanism that causes
brain cells to die from stroke, researchers have found a way to keep brain
cells alive for more than three hours without oxygen and nutrients.
The researchers found that when brain cells are deprived of oxygen and vital
nutrients as a result of stroke, a channel called TRPM7 that resides on the
surface of those brain cells is activated, triggering a lethal chain
reaction. The researchers report that they have found a way to disrupt this
cycle by interfering with the channel's activity. While brain cells can only
survive for a few minutes without oxygen, interfering with the activity of
TRPM7 allows brain cells to survive for more than three hours without oxygen
and vital nutrients. The researchers predict that it will take about three
years to develop medications bases on these findings. The study is reported
in the journal <a
href="http://www.cell.com/content/article/abstract?uid=PIIS0092867403010171"
>Cell</a>.
		http://www.betterhumans.com/News/news.aspx?articleID=2003-12-24-4

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