X-Message-Number: 24254
From: "G. Urban" <>
Subject: An innovation in cryonics
Date: Wed, 16 Jun 2004 16:16:29 +0200

I have an idea about cryonics. The main problem with cryonics is, that 
people don't realize, that the frozen (and vitrified) patients are alive. 
The main aim of cryonics research therefore must be, to verify the viability 
of a deep cooled whole CNS. It is not enough to verify the viability of a 
hyppocampal slice, although it's much easier to do because of higher 
relative surface. All people would agree, that a simple injection is 
non-fatal, although most people think, that freezing is fatal. What if you 
would amplify the relative surface ratio of a brain by using the very 
conservative method of ijection? Of course, many injections at a time. You 
could inject the perfusion agents directly into the brain, thus achieving a 
perfect distribution of the chemicals, which can even be specially mixed for 
each different part of the brain. Unfortunately many blood vessels will be 
hurt, but this, together with those cells, that were directly hurt, is much 
lesser damage, than frost-related cell damage. (I mean, biologically, maybe 
it does some informatical damage, but every brain surgery does. If the 
injection needles are small enough, the info and blood vessel damage would 
be relatively small.) Even a short viability after resuscitation in a brain 
of an experimental animal would clearly show, that cryo patients are living 
persons, and therefore it would basically redefine the status and acceptance 
of cryonics.

But even long viability can be achieved after resuscitation, and _without 
any nanotechnology_, because the hurted blood vessels could be artificially 
closed with some kind of surgical glue, when the needles are taken out of 
the brain. (This would only happen after rewarming. The needles are frozen 
/I mean, vitrified/ into the brain.) The process is appx. as following: 
1.:Initial cooling and washout of the blood. 2.: While the needles are 
slowly moved into the brain, cryoprotectants are pumped in through the 
needles, and maybe water would be removed through every second needle. 3.: 
Cooling. This could preferably happen by the flow of a cooling agent (even a 
gas) through the needles. The needles, of course, are already fully crossing 
the brain at that time, and they can get closer to each other, as the brain 
is shrinking. There can be problems, because of the different shrinking rate 
of the brain and the needles, but these can be solved. The brain looses the 
heat at all places with the same speed, so there are no inner cracks. (The 
flowing direction of the cooling agent must be changed, each time there are 
temperature asimmetries.) 4.: Storage (With the needles left in the brain) 
5.: Resuscitation. This is appx. the opposite of the above mentioned 
procedures. 5./1.: Initial Rewarming (Preferably with gas through the 
needles.) 5./3.: Chemical threatment from the point of thawing until the 
achievement of the minimal temperature of viability. (Preferably somewhat 
below body temperature.) 5./4.: Removal of the needles while injecting a 
surgical glue to close the blood vessels. 5./5.: Reperfusion with blood. 
(5./6.: Rejoining with a cloned or robotic body, this is yet impossible, 
although a brain transplant to a body of a brain-dead person is not science 
fiction.) I hope this idea can help the science of cryonics.

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