X-Message-Number: 24429
Date: Sat, 24 Jul 2004 21:09:37 -0700 (PDT)
From: Doug Skrecky <>
Subject: ...mortality rate decreased 4.1 times...

Neuro Endocrinol Lett. 2003 Jun-Aug;24(3-4):233-40.
Peptides of pineal gland and thymus prolong human life.
  OBJECTIVES AND DESIGN: Researchers of the St. Petersburg Institute of
Bioregulation and Gerontology of the North-Western Branch of the Russian
Academy of Medical Sciences and the Institute of Gerontology of the
Ukrainian Academy of Medical Sciences (Kiev) clinically assessed the
geroprotective effects of thymic (Thymalin) and pineal (Epithalamin)
peptide bioregulators in 266 elderly and older persons during 6-8 years.
The bioregulators were applied for the first 2-3 years of observation.
RESULTS: The obtained results convincingly showed the ability of the
bioregulators to normalize the basic functions of the human organism, i.e.
to improve the indices of cardiovascular, endocrine, immune and nervous
systems, homeostasis and metabolism. Homeostasis restoration was
accompanied by a 2.0-2.4-fold decrease in acute respiratory disease
incidence, reduced incidence of the clinical manifestations of ischemic
heart disease, hypertension disease, deforming osteoarthrosis and
osteoporosis as compared to the control. Such a significant improvement
in the health state of the peptide-treated patients correlated with
decreased mortality rate during observation: 2.0-2.1-fold in the
Thymalin-treated group; 1.6-1.8-fold in the Epithalamin-treated group;
2.5-fold in the patients treated with Thymalin plus Epithalamin as
compared to the control. A separate group of patients was treated with
Thymalin in combination with Epithalamin annually for 6 years and their
mortality rate decreased 4.1 times as compared to the control.
CONCLUSIONS: The obtained data confirmed the high geroprotective efficacy
of Thymalin and Epithalamin and the expediency of their application in
medicine and social care for health maintenance and age-related pathology
prevention in persons over 60 to prolong their active longevity.

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