X-Message-Number: 24795
Date: Mon, 11 Oct 2004 17:54:52 -0700 (PDT)
From: Doug Skrecky <>
Subject: negligible senescence research

Ann N Y Acad Sci. 2004 Jun;1019:518-20
Emerging area of aging research: long-lived animals with "negligible
senescence".
  Field observations have suggested for quite some time that certain
fish, turtles, and invertebrates have extremely long maximum life span
potential. Age validation techniques have since confirmed these
observations, but scientific analysis to understand the genetic and
biochemical basis of this longevity has occurred only recently. The
Centenarian Species and Rockfish Project now encompasses 13 pilot
research projects, including such diverse investigations as histology, a
cDNA library, and mitochondrial mutation analysis. In this document, the
term "negligible senescence" is defined, and its background is given; age
validation techniques are listed, and the various projects to date,
including research results, are summarized.

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