X-Message-Number: 25818 From: Date: Fri, 18 Mar 2005 01:40:33 EST Subject: Re: LTP About Long Term Potentiation linked to fiber proteins: It is known that at least some forms of LTP originate in the presynaptic axon terminal. These LTP are produced by an augmented probability of vesicle release. Given that vesicle redy to be released are storred near the cell membrane by cytotransport along fibers, if these fibers are disabled, the vesicles can't get to the release sites and these ones are so depleted. The release probability is then severly limited and there is no room for LTP. The same result could be produced by disabling any step in the neurotransmitter production or recycling or by any defect in the release or recycling of the vesicles. Yvan Bozzonetti. Content-Type: text/html; charset="US-ASCII" [ AUTOMATICALLY SKIPPING HTML ENCODING! ] Rate This Message: http://www.cryonet.org/cgi-bin/rate.cgi?msg=25818