X-Message-Number: 26294
Date: Mon, 6 Jun 2005 22:29:51 -0700 (PDT)
From: Doug Skrecky <>
Subject: 177'th update on fly longevity experiments

     This is the 177'th update of my fly longevity experiments. Average
 temperature was 22.2 C during this run. Estimated maximal longevity using
 the formula (363 - T*11.2) is 115 days.
     In this run, I take another look at urea, which at an 1/8 tsp dose
 was associated with an increased average, but not maximal longevity in
 run #173. Lactoferrin is an iron chelator, and triphala is a potent
 superoxide scavenger.
     Lactoferrin turned out to be dud, but a couple of flies fed a high
 dose  of triphala did outlive the controls, although this might still
 have been due to chance.
     Urea at the 1/8 tsp dose was helpful once again, and the 1/16 tsp
 dose appeared to be even better. Low doses of urea might be reducing
 mating frequency, and thereby improving average longevity by reducing
 exposure to mating associated mortality. Urea is being further examined
 in run #192, and if this benefit is further confirmed, low dose urea may
 become a standard additive in future to all fly runs.

 Run #177                    Percent Survival on Day
 supplement          6 18 28 37 44 52 61 69 79 87 93 100 108 116
 _______________________________________________________________
 control one        96 74 57 57 57 52 49 26 13  9  4   0   -   -
 control two        97 55 55 52 52 46 33 24 15  9  3   0   -   -
 lactoferrin 63 mg  90 61 61 61 58 46 36 26 19 16 10   0   -   -
   "        250 mg 100 68 64 59 50 27  9  5  5  5  0   -   -   -
 triphala 63 mg     97 74 65 59 56 44 24 15  6  3  0   -   -   -
   "     250 mg    100 65 62 62 57 51 41 27 27 16  8   5   3   0
 urea 1/16 tsp     100 94 86 81 75 72 64 53 42 39 22   0   -   -
   "  1/8 tsp       96 72 64 64 60 56 52 40 28 20  8   0   -   -
   "  1/4 tsp      100 89 89 82 75 68 46 39 18 11  4   0   -   -
   "  1/2 tsp       97 74 68 68 68 29 16 10  3  0  -   -   -   -
   "  1 tsp        100 94 75 63 41 22  3  0  -  -  -   -   -   -

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