X-Message-Number: 26316 From: "Basie" <> Subject: Cross linking can be reversed Date: Sat, 11 Jun 2005 23:45:59 -0400 "Firstly, cross-linking of structural proteins seems to be dramatically reversed by a chemical called ALT-711, or, more technically, phenacyldimethylthiazolium chloride, which restores the arteries, cartilage, and skin of experimental animals to youthful elasticity and is currently in clinical trials (16). " 16. S. Vasan, P. G. Foiles, H. W. Founds, Therapeutic potential of AGE inhibitors and breakers of AGE protein cross-links. Expert Opin. Investig. Drugs 10, 1977-1987 (2001). ____________________________________________________________________________________ The above quote is from A. de Grey. If cross linking can be reversed. Why just do freezing? Clearly freezing plus cross linking is better. If there is an increase in temperature cross linking can be a life saver. Basie Rate This Message: http://www.cryonet.org/cgi-bin/rate.cgi?msg=26316