X-Message-Number: 26740 From: Subject: Brain Vitrification Date: Sat, 30 Jul 2005 22:01:40 +0000 --NextPart_Webmail_9m3u9jl4l_12276_1122760900_0 In Cryomsg 26716, Robert Ettinger wrote: > As far as I know, nobody--nobody, nobody, nobody--has yet vitrified a whole mammalian brain and quantified the results in various segments and subsegments. In Cryomsg 26723, Joe Waynick replied > Mr. Ettinger makes an important point when he says nobody--has yet vitrified a whole mammalian brain and quantified the results in various segments and subsegments. I think that is an important and necessary bit of work and I want our membership to know that Alcor is currently considering those issues as a research project. These statements are mistaken. Shortly before Joe Waynick became Alcor's new CEO, Alcor in fact presented the results of a whole mammalian brain vitrification study with detailed electron microscopy results in multiple brain regions at the 10th Congress of The International Association of Biomedical Gerontology at Queen's College, Cambridge, England. http://www.alcor.org/Library/html/cambridge.html Last year this work appeared in a paper in the journal Annals of the New York Academy of Sciences http://www.alcor.org/Library/html/annals.html These results have since been replicated by cooling brains at human cryopatient core cooling rates to below the glass transition temperature (vitrification) and back again without signs of ice formation on electron micrographs. The results are further confirmed as credible by the presentation of data at this years Society for Cryobiology meeting showing that the vitrification solution used, M22, can be vitrified in large volumes cooling at only 0.1 degC per minute without ice formation. Whole mammalian brains can and have been structurally vitrified, even at very slow cooling rates. ----Brian Wowk --NextPart_Webmail_9m3u9jl4l_12276_1122760900_0 Content-Type: text/html [ AUTOMATICALLY SKIPPING HTML ENCODING! ] Rate This Message: http://www.cryonet.org/cgi-bin/rate.cgi?msg=26740