X-Message-Number: 26767
Date: Thu, 4 Aug 2005 19:48:28 -0700 (PDT)
From: Doug Skrecky <>
Subject: 185'th update on fly longevity experiments

     This is the 185'th update of my fly longevity experiments. Average
 temperature was 23.9 C during this run. Estimated maximal longevity using
 the formula (363 - T*11.2) is 95 days.
     As part of a standard screening process, I like to check anything
 that exerts neuroprotective effects in any animal species. Spirulina
 algae has effectively blocked brain aging in Fisher 344 rats. (J
 Neuroscience 22(14): 6114-6120) Hence here I test a variety of algae.
     Alas, neither chlorella nor spirulina algae offered any benefit.
 The middle (1/4 tsp) dose of blue-green algae appeared to offer some
 benefit on average, but not maximum longevity. However this may have been
 due to chance.
     A wide variety of antioxident rich foods (apples, blueberrys,
 spinach, spirulina, strawberrys) have slowed or even halted brain aging
 according to various criteria in rodents. It is possible that this
 may merely reflect how poor the control commercial rodent chow is. In any
 case I have consistently found no longevity benefit for such foods when
 they are mixed with 4-24 fly food.

 Run #185              Percent Survival on Day
 supplement           7 17 25 31 38 46 54 64 71 81 88
 ____________________________________________________
 control one         86 86 76 76 71 52 43 29 14  5  0
 control two         86 62 67 67 57 52 38 10  5  5  0
 blue-green 1/16 tsp 96 72 60 56 56 52 40 28  8  0  -
   "(algae) 1/4 tsp  96 83 78 78 74 70 65 52 30 13  0
   "        1 tsp    83 72 61 61 56 44 33 17 11  0  -
 chlorella 1/16 tsp  90 68 68 58 53 37 37 32 16  0  -
   "       1/4 tsp   91 91 76 62 38 29 19 14 14  5  0
   "       1 tsp     83 61 50 50 50 39 39 33 28 11  0
 spirulina 1/16 tsp  77 46 54 46 46 31 23 23 15  0  -
   "       1/4 tsp   96 83 61 44 39 30 26 17  4  0  -
   "       1 tsp     77 53 47 47 24 24 18 18  6  0  -

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