X-Message-Number: 3651 Date: 09 Jan 95 13:10:57 EST From: yvan Bozzonetti <> Subject: CRYONICS :Wizard's toad spittle recipe Toad spittle is a well known and essential element in many magical recipe. Given the magical promise of cryonics, I think any serious cryonics work must include that basic element. So I suggest to include toad spittle in patient wash out solution. Some extracts from snake heads would be of some interest too. (No, I have not to use emoticons here). Now I try to convince nonmagical people with some words at their level: One part of the inner cell scafolding is made from myosine fibers; Most organels inside the cell are anchored to these fibers. Such fibers work as extended spring and need some energy input to remain in this elongated state. When cells are cooled down, Adenosine TriPhosphate (ATP) the energy currency of the cell is no more produced or used, so the spings shrink, pulling down all cell element the ones against the others. The destructive effect is very big and reduces the cell survival potential. Some poisons, found in snake venons or toad skin secretion, for example the well known curare exploited by Amazon's indians, are muscular paralyser working on the molecule of interest here. With them, even without energy input, even at low temperature, the fibers don't retract. Adding curare to a cell culture before cooling may be a important element in the survival process. Who will experiment this ? It could be far more useful to do it that killing one more dog. Y.B. Rate This Message: http://www.cryonet.org/cgi-bin/rate.cgi?msg=3651