X-Message-Number: 4392
Date: Fri, 12 May 1995 07:32:52 -0700 (PDT)
From: "Joseph J. Strout" <>
Subject: Data required for uploading

> From: Eugen Leitl <>
> 

> > Just how much memory depends, of course, on what there is about yourself 
that

> > you consider essential, and on how far down in the hierarchy of neural parts

> > you wish to go ie. atoms? molecules (remember lots of biochemicals are quite
> 
> Single neurons/synapses (weighted-edge graph information) will do.

I suspect that this is highly oversimplistic.  To configurate an accurate 
neural emulator, you need at least (a) detailed morphological data, and 
(b) information on the distribution of ion channels on the cell 
membranes.  At least, this is the information needed by current cell-
level simulators.  It may be possible to reduce this requirement somewhat 
*if we can also take physiological measurements*, but this remains to be 
shown, and besides, you can get physiological measurements from dead 
tissue.  But I wholly agree with your success criterion:

> Provided I/my friends do not notice the difference between my original
> deceased me and the simulation it is accurate. At least accurate enough
> for me. 

You then tease us with:

> By the way, sometimes in the past I said that nondestructive scan is
> probably impossible. I have to reduce that claim. A kind of technology
> based in SQUID interferometry (several arrays of integrated SQUDS hooked to
> broadband data acquisition recorders, e.g. RAID arrays) might produce
> the necessary resolution and information on dynamic behaviour both.

Please please please take the time to dig up a reference or two for us.  
This could be very important, but we can't evaluate it properly without 
seeing some original papers.

-- Joe

,------------------------------------------------------------------.
|    Joseph J. Strout           Department of Neuroscience, UCSD   |
|               http://sdcc3.ucsd.edu/~jstrout/    |
`------------------------------------------------------------------'


Rate This Message: http://www.cryonet.org/cgi-bin/rate.cgi?msg=4392