X-Message-Number: 4981 Date: Fri, 13 Oct 1995 14:05:32 -0700 (PDT) From: Doug Skrecky <> Subject: I agree with Mike Darwin The following abstract is from an article which examined the condition of excisions from the frontal part of the cerebral cortex of 9 humans 3 hours after death due to long-termed ischemic heart disease. "Ultrastructural Changes of Neurons in Dependence on the Death Cause in Human Brain" (Functional and Developmental Morphology Vol.2 No.4 231-234 1992 ABSTRACT: Autolytic changes in animal neurons 3 hours postmortum were compared with the changes in human material taken from patients with ischemic heart disease. Relatively homogenous neuroplasm in the animal material was observed and the nuclei and nucleoli were present as well. Light artificial spaces were visible around the neurons. Marked vacuolization was seen in all cases of the human material. In some cases the nucleus with the nucleolus and mitochondria were still preserved. Majority of the neurons did not reveal the nucleolus and chromatin in their nuclei; destruction of the organelles and homogenization of the neuroplasm were dominent. We assume that the specific changes in the brain caused by the ischemic heart disease are different in comparison with the autolytic postmortal changes. Rate This Message: http://www.cryonet.org/cgi-bin/rate.cgi?msg=4981