X-Message-Number: 4981
Date: Fri, 13 Oct 1995 14:05:32 -0700 (PDT)
From: Doug Skrecky <>
Subject: I agree with Mike Darwin

     The following abstract is from an article which examined the
 condition of excisions from the frontal part of the cerebral cortex of 9
 humans 3 hours after death due to long-termed ischemic heart disease. 

 "Ultrastructural Changes of Neurons in Dependence on the Death Cause in
 Human Brain" (Functional and Developmental Morphology Vol.2 No.4 231-234
 1992

 ABSTRACT: 
     Autolytic changes in animal neurons 3 hours postmortum were compared
 with the changes in human material taken from patients with ischemic
 heart disease. Relatively homogenous neuroplasm in the animal material
 was observed and the nuclei and nucleoli were present as well. Light
 artificial spaces were visible around the neurons. Marked vacuolization
 was seen in all cases of the human material. In some cases the nucleus
 with the nucleolus and mitochondria were still preserved. Majority of the
 neurons did not reveal the nucleolus and chromatin in their nuclei; 
 destruction of the organelles and homogenization of the neuroplasm were
 dominent. We assume that the specific changes in the brain caused by the
 ischemic heart disease are different in comparison with the autolytic 
 postmortal changes. 


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