X-Message-Number: 5290
Date:  Tue, 28 Nov 95 23:07:36 
From: mike <>
Subject: SCI.CRYONICS MRI microscopy

Can anyone knowledgeable in MRI comment on the following?
What I am interested in is the possibility of imaging a tissue prism, 
approximately a cube 100 micrometers on a side, down to 1 micrometer 
resolution (that is, 1% field of view resolution). In this way it 
should be possible to observe postmortem changes in brain tissue as 
they happen, by repeated examination of the same piece of tissue, 
which is impossible under current fixation and staining methods.
I'm hoping that 1 micrometer resolution would allow a 
glimple of dendritic spines, while the size of the tissue prism 
overall woud provide a reasonable context.

Mike Perry 


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