X-Message-Number: 5354 From: (Brian Wowk) Newsgroups: sci.cryonics Subject: Re: High Pressure Cryonics Date: 5 Dec 95 20:47:27 GMT Message-ID: <> References: <> <4a0mf5$> In <4a0mf5$> (JensTroll) writes: JT>I question how "pure hydrostactic pressure" using a liquid even at levals JT>as high as 2-3000 barr could cause damage to tissues. JT>I suspect that the damage was caused by 1) too rapid application or JT>release of pressure, 2) too high partial pressures of reactive gasses JT>disolved in the liquid (especially oxygen), 3) too high partal pressures JT>of any gasses combined with a too rapid release of pressure could cause a JT>lot of damage. Has this research addressed these issues???? Unfortunately my limited knowledge on this subject is second hand. Still, why do you reject protein denaturation as a damage mechanism? Obviously the nature of hydrogen bonds changes with hydrostatic pressure, or you wouldn't get all those bizarre types of ice forming in the first place. If you alter hydrogen bonding in water with pressure, you sure as heck will alter the hydrogen bonding that determines the conformation of proteins. ---Brian Wowk Rate This Message: http://www.cryonet.org/cgi-bin/rate.cgi?msg=5354