X-Message-Number: 6125
Date: Sun, 28 Apr 1996 23:49:48 -0700 (PDT)
From: Doug Skrecky <>
Subject: Re: Low calorie or low weight? (fwd)

Here's something cryonetters might find interesting.   Doug

---------- Forwarded message ----------
Date: Thu, 25 Apr 1996 21:17:09 -0700 (PDT)
From: Doug Skrecky <>
Subject: Re: Low calorie or low weight?

On Thu, 25 Apr 1996, Ian Eiloart wrote:
> My question is this. Are there any animal experiments that prove that body
> weight is important variable here?
> Humans can adjust their weight by diet or exercise. Are there animal
> experiments that test this variable? 
> Can I still eat a lot (well a reasonable amount) if I get my weight down by
> exercising, and still hope to live longer?

Unfortunately exercise does not possess the age retarding effect of 
caloric restriction. Rats that lose weight by exercising do not live as 
long as those on a diet. The following chart derived from Journal of Applied 
Physiology 70(4):1529-1535 1991 tells the tale:

A: controls          875   1200
B: exercised         978   1208
C: 30% restricted   1056   1322 (same weight as B)
D: exercised &       995   1328
   30% restricted
E: 46% restricted   1088   1341 (same weight as D)

As can be seen exercising can even reduce the average (but not maximum) 
lifespan of restricted Long Evans Rats. However the real action is not 
with exercise or caloric restriction, but instead it is with life 
extending supplements. The following can be added to the above chart from 
Medical Hypotheses Vol.43 253-265 1994, which reported the effect of 
chromium picolinate on the lifespan of ad libitum fed Long Evans rats.

F: chromium         1320   1440

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