X-Message-Number: 6991
From:  (Brian Wowk)
Newsgroups: sci.cryonics
Subject: Re: Solution to Glycerol Toxicity
Date: 27 Sep 96 17:43:33 GMT
Message-ID: <>
References: <52fh38$>

In <52fh38$>  (Doug Skrecky) writes:

>     Glycerol is metabolized to formaldehyde by living tissue.

> the antioxident propyl gallate inhibited formaldehyde production...

> It appears that the addition of propyl gallate to all glycerol 
> solutions currently used by cryobiologists and cryonics companies
> is mandated.

	Is there any evidence that glycerol is metabolized at
cryothermic temperatures?  As far as I'm aware, glycerol toxicity
in cryobiology is due to the direct action of glycerol itself.

	Of course this may all be academic given the renewed
interest in non-glycerol CPAs inspired by Visser.  None of
the most promising organ cryopreservation technologies now
use glycerol.  Glycerol's days in cryonics are clearly numbered. 

 ***************************************************************************
 Brian Wowk          CryoCare Foundation               1-800-TOP-CARE
 President           Human Cryopreservation Services   
    http://www.cryocare.org/cryocare/
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