X-Message-Number: 7138 Date: Wed, 13 Nov 1996 18:53:46 -0800 (PST) From: Doug Skrecky <> Subject: DNA-RNA-Chloroform Injections Increase Life Span 144% (fwd) A little off topic, but I think many cryonetters would like to see this post. Sincerely Doug Weekly injections of DNA solution in water saturated with chloroform (3 mg/ml) plus ordinary RNA have dramatically increased the life span of rats. Ten rats from an unidentified strain with a reported maximum life span of 900 days were selected for the experiment when they were 750 days old. The five control animals all died before 900 days, as expected. It was reported that after 84 days (12 weeks) the five injected rats looked remarkably "younger", were more "lively" and had gained weight. Of the injected rats 4 died aged between 1600 and 1900 days, while the fifth lived to 2200 days. (1) An increase of maximum life span by 144% from 900 to 2200 days with a treatment which was only commenced in old (750 day) animals is (to be frank) simply unbelievable. A weighted average life span for the five injected animals of about 1850 days is likewise unprecedented. If these results can be replicated they would constitute the most effective anti-aging intervention in rodents by a large margin. For example one experiment investigating the effect of life long 40% calorie restriction in Fisher 344 rats found that maximum life span was increased by 38% from 941 to 1296 days. A copy of the DNA-RNA-CHLOROFORM injection experiment using humans would mean that injections were started in five 75 year olds and four of them died at between 160 to 190 years of age, while the final survivor lived to 220 years of age. This experiment needs to be replicated in rats first! (1) "Prolongation of the Life Span in Rats" Journal of the American Geriatrics Society 21(10) 450-451 October 1973 (2) "Nutritional Influences on Aging of Fisher 344 Rats: I. Physical, Metabolic and Longevity Characteristics" Journal of Gerontology 40(6) 657-670 1985 Rate This Message: http://www.cryonet.org/cgi-bin/rate.cgi?msg=7138