X-Message-Number: 8484 From: Date: Thu, 21 Aug 1997 20:39:08 -0700 (PDT) Subject: Tom Shapard's suggestion in CryoNet #8474, "Catching the Wave" >I call it "Catching the Wave". Maybe becasue I'm from CA and too surf >influence, but it seems apt to me. It means living long enough so that the >wave of medical technology comes up behind you, extending your life still >more, carring a bit farther into the future, where still improved >technology takes you all the way in to indefinite lifespan. >Tom Shapard <> Although I am not a surfer, I really like that term, as it describes perfectly the way I feel about my personal assessment on how to reach an indefinite lifespan. - Point: Mike Perry's message #8482: "The cloning of an important human telomerase gene has been reported in *Science* ("Telomerase catalytic subunits from fission yeast and human: a unique branch of reverse transcriptases," *Science* Aug. 15, 1997.) Two collaborating groups were involved, Geron Corp. and the University of Colorado, Boulder. According to Thomas Cech of UC Boulder, "The cloning of the active center of telomerase is a major milestone ... (Rest of the text deleted, but can be read in Message # 8482) - Point: Chromos Molecular Systems Inc. Chromos Molecular Systems Inc. The company's business is to develop and produce engineered mammalian artificial chromosomes, which are stable... http://www.chromos.com/ - size 2K - 25-Feb-97 - English (I have just tried to get into their site and get error messages. I believe, that they are in the process of moving to new premises). As the above text indicates, they have as I understand been successful in producing artificial animal chromosomes and are already in the process of marketing them. My earlier enquiry as to the presence of telomeres went unanswered, I guess due to my lack of scientific credentials.) - Point: The recent announcement by that group of Australian scientists, who have developed that little sniffer, which includes its a molecular size switch, which is only 1.5nm long. That makes it only 1/200th of the lenght of your average bacterium. As they do not say anything about self- replication in any of the text, which I read, I assume, that that has not yet been achieved. Nevertheless most of us have not expected this type of technology, which produced that switch for another ten years. With these and a number of other developments in the fields of medicine and biotechnology, I believe that it is not unrealistic to expect major breakthroughs in rejuvination at the cellular level within 50 to 70 years. Now to catching my own personal 'wave': I am now 63 years old of excellent health and in better physical shape than many a 40 year old. This gives me reason to believe, that I have the inherent capacity to make it to age 90, i.e. another 27 years If we can believe Messrs. Dr. William Regelson and Dr. Ronald Klatz, then present day techniques of hormone replacement, and vitamin supplements etc. will give me (the next 'wave'?): another 15 years ------- --------- Prelim. Total: another 42 years By this conjecture I have 42 more years to live and anti-aging medicine has 42 years to come up with solutions to keep me alive an additional 8 to 28 years after that (the last 'wave'?), or until I am somewhere between 113 and 133 years old. :) Okay, so I am dreaming, but is there anybody in this group who will declare this scenario as outright impossible? The trick is to get onto the 'wave' of new technologies to be carried forward towards the goal of indefinite life-span in the best physical condition possible. All the best, Olaf Rate This Message: http://www.cryonet.org/cgi-bin/rate.cgi?msg=8484