X-Message-Number: 8990
Subject: Re: many of ginkgo biloba's effects are mediated by bilobalide
Date: Mon, 12 Jan 1998 09:43:33 -0600
From: Will Dye <>

Doug Skrecky writes:

> A marked increase of choline release from rat hippocampal 
> slices was observed when the slices were superfused with 
> oxygen-free buffer, indicating hypoxia-induced hydrolysis 
> of choline-containing phospholipids.  This increase 
> of choline release was suppressed by bilobalide, 
> [...]   We conclude that ginkgo extracts can suppress 
> hypoxia-induced membrane breakdown in the brain, and that 
> bilobalide is the active constituent for this effect. 

I sort-of followed your post (from Klein, Chatterjee, and 
Loffelholz), but I'm not sure.  What do you feel is the 
signifigance of this article to cryonics and/or life extension?  

--Will

(BTW, I have a personal interest in Gingko because I'm 
considering buying DMAE/Ginkgo or some other substances 
reputed to improve cognitive performace, from Saul Kent's 
company.  My concentration abilities are not what they 
should be, especially for a computer programmer.)

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